NRBP2

Entrez Summary: N/A
UniProt Summary: May regulate apoptosis of neural progenitor cells during their differentiation. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Pkinase Tyr
Pkinase

negative regulation of macroautophagy
endomembrane system
negative regulation of autophagy
negative regulation of neuron apoptotic process
regulation of macroautophagy
negative regulation of neuron death
regulation of neuron apoptotic process
endoplasmic reticulum to Golgi vesicle-mediated transport
negative regulation of cellular catabolic process
negative regulation of catabolic process
regulation of neuron death
regulation of autophagy
protein serine/threonine kinase activity
Golgi vesicle transport
regulation of cellular catabolic process
negative regulation of apoptotic process
negative regulation of programmed cell death
protein phosphorylation
regulation of catabolic process
negative regulation of cell death
neuron differentiation
phosphorylation
ATP binding
intracellular transport
generation of neurons
regulation of apoptotic process
regulation of programmed cell death
neurogenesis
regulation of cell death
intracellular signal transduction
establishment of localization in cell
vesicle-mediated transport