NUDT19

Entrez Summary: N/A
UniProt Summary: Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched- chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

acyl-CoA hydrolase activity
peroxisomal matrix
protein localization to peroxisome
protein targeting to peroxisome
establishment of protein localization to peroxisome
peroxisomal transport
peroxisome organization
fatty acid catabolic process
monocarboxylic acid catabolic process
cellular lipid catabolic process
carboxylic acid catabolic process
organic acid catabolic process
lipid catabolic process
fatty acid metabolic process
protein targeting
establishment of protein localization to organelle
small molecule catabolic process
cellular component
monocarboxylic acid metabolic process
protein localization to organelle
carboxylic acid metabolic process
cellular lipid metabolic process
intracellular protein transport
oxoacid metabolic process
organic acid metabolic process
lipid metabolic process
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
small molecule metabolic process
organic substance catabolic process
cellular catabolic process
establishment of localization in cell
nitrogen compound transport