NXPE1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Olaparib 4μM R08 exp512	-2.18
GSK591 2.6μM R03 exp128	-1.96
BI-2536 0.0042μM R03 exp95	-1.74
PF-06409577 20μM R07 exp389	1.83
CR131-b 0.005μM R08 exp474	1.87
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	1.92
Thalidomide 20μM R07 exp406	2.06

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution