OPA3

Gene Information
  • Official Symbol: OPA3
  • Official Name: outer mitochondrial membrane lipid metabolism regulator OPA3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 80207
  • UniProt: Q9H6K4
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
  • UniProt Summary: May play some role in mitochondrial processes.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 17777
  • Expression level (log2 read counts): 5.86

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1