PERP

Gene Information
  • Official Symbol: PERP
  • Official Name: p53 apoptosis effector related to PMP22
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 64065
  • UniProt: Q96FX8
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 8401
  • Expression level (log2 read counts): -1.17

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1