PF4V1

Entrez Summary: N/A
UniProt Summary: Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro). {ECO:0000269|PubMed:15459074}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Nifuroxazide 1μM R01 exp51	-2.08
PFI-2 4μM R05 exp239	1.81

chemokine activity
antimicrobial humoral immune response mediated by antimicrobial peptide
chemokine-mediated signaling pathway
neutrophil chemotaxis
granulocyte chemotaxis
cellular response to chemokine
response to chemokine
neutrophil migration
granulocyte migration
antimicrobial humoral response
myeloid leukocyte migration
platelet activation
leukocyte chemotaxis
heparin binding
cellular response to lipopolysaccharide
cellular response to molecule of bacterial origin
cell chemotaxis
cellular response to biotic stimulus
blood coagulation
coagulation
hemostasis
response to lipopolysaccharide
response to molecule of bacterial origin
humoral immune response
leukocyte migration
wound healing
regulation of body fluid levels
inflammatory response
cellular response to lipid
chemotaxis
taxis
response to wounding
cytokine-mediated signaling pathway
response to bacterium
response to lipid
cell migration
cellular response to cytokine stimulus
cellular response to oxygen-containing compound
cell activation
localization of cell