PHF12

Gene Information
  • Official Symbol: PHF12
  • Official Name: PHD finger protein 12
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 57649
  • UniProt: Q96QT6
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA. {ECO:0000269|PubMed:11390640, ECO:0000303|PubMed:11390640}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1782
  • Expression level (log2 read counts): 6.55

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1