PHF13

Entrez Summary: N/A
UniProt Summary: Modulates chromatin structure. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis. {ECO:0000269|PubMed:19638409}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
R-DABN 8μM R03 exp111	1.84
Tunicamycin 0.04 to 0.125μM on day4 R07 exp420	1.96

mitotic chromosome condensation
chromosome condensation
methylated histone binding
mitotic sister chromatid segregation
sister chromatid segregation
mitotic nuclear division
DNA packaging
nuclear chromosome segregation
chromosome segregation
nuclear division
DNA conformation change
organelle fission
chromatin binding
cell division
mitotic cell cycle process
mitotic cell cycle
chromatin organization
cell cycle process
chromosome organization
cell cycle