PKD2L2

Official Symbol: PKD2L2
Official Name: polycystin 2 like 2, transient receptor potential cation channel
Aliases and Previous Symbols: N/A
Entrez ID: 27039
UniProt: Q9NZM6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: May function as a subunit of a cation channel and play a role in fertilization.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
ABT-702 5μM R06 exp261	-2.11
Curcumin 6.5μM R06 exp277	-1.92

Ion trans
PKD channel

detection of mechanical stimulus
calcium channel activity
detection of external stimulus
detection of abiotic stimulus
calcium ion transmembrane transport
response to mechanical stimulus
calcium ion transport
divalent metal ion transport
divalent inorganic cation transport
inorganic cation transmembrane transport
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
detection of stimulus
calcium ion binding
cation transport
ion transmembrane transport
response to abiotic stimulus
transmembrane transport
ion transport
membrane