PPP1R1B

Gene Information
  • Official Symbol: PPP1R1B
  • Official Name: protein phosphatase 1 regulatory inhibitor subunit 1B
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 84152
  • UniProt: Q9UD71
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
  • UniProt Summary: Inhibitor of protein-phosphatase 1.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 6215
  • Expression level (log2 read counts): -0.18

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1