PRTG

Entrez Summary: N/A
UniProt Summary: May play a role in anteroposterior axis elongation. {ECO:0000250|UniProtKB:Q2EY15}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
SGC0649 7μM R03 exp150	-1.92
Tunicamycin 0.04μM R07 exp418	-1.9

I-set
fn3

signaling receptor activity
negative regulation of neurogenesis
negative regulation of nervous system development
negative regulation of cell development
protein homooligomerization
protein complex oligomerization
negative regulation of cell differentiation
regulation of neurogenesis
regulation of nervous system development
regulation of cell development
negative regulation of developmental process
negative regulation of multicellular organismal process
generation of neurons
protein-containing complex assembly
extracellular space
neurogenesis
regulation of cell differentiation
protein-containing complex subunit organization