PTCH2

Gene Information
Function Summary
  • Entrez Summary: This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009].
  • UniProt Summary: May have a role in epidermal development. May act as a receptor for Sonic hedgehog (SHH).

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 10808
  • Expression level (log2 read counts): 1.83

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1