PTCHD4

Gene Information
  • Official Symbol: PTCHD4
  • Official Name: patched domain containing 4
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 442213
  • UniProt: Q6ZW05
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down- regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4-expressing cells. {ECO:0000269|PubMed:25296753}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 6324
  • Expression level (log2 read counts): 2.44

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1