RBMS1

Entrez Summary: N/A
UniProt Summary: Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
RO-3306 3 to 4μM on day4 R04 exp165	-1.96
HMS-I2 10μM R06 exp288	2.36

poly(A) binding
poly(U) RNA binding
mRNA 3-UTR binding
double-stranded DNA binding
single-stranded DNA binding
ribonucleoprotein complex
DNA replication
RNA processing
RNA binding
RNA metabolic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
gene expression