RBMXL1

Entrez Summary: N/A
UniProt Summary: RNA-binding protein which may be involved in pre-mRNA splicing. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 22/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	3/28
bone	0/26
breast	1/33
central nervous system	1/56
cervix	0/4
colorectal	2/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	1/21
liver	0/20
lung	0/75
lymphocyte	1/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	1/15
prostate	1/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
PT-1 25μM R07 exp392	-1.79
UMK57 1μM R01 exp59	1.91

RBM1CTR
RRM 1

positive regulation of mRNA splicing, via spliceosome
positive regulation of mRNA processing
positive regulation of RNA splicing
positive regulation of mRNA metabolic process
spliceosomal complex
regulation of mRNA splicing, via spliceosome
regulation of RNA splicing
regulation of mRNA processing
ribonucleoprotein complex
regulation of mRNA metabolic process
RNA splicing
mRNA processing
mRNA metabolic process
RNA processing
RNA binding
RNA metabolic process
positive regulation of RNA metabolic process
positive regulation of nucleobase-containing compound metabolic process
positive regulation of gene expression
gene expression