RHCG

Entrez Summary: N/A
UniProt Summary: Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion. {ECO:0000269|PubMed:11062476, ECO:0000269|PubMed:14761968, ECO:0000269|PubMed:15929723, ECO:0000269|PubMed:16477434}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

transepithelial ammonium transport
ammonium transmembrane transporter activity
amine transport
ammonium transmembrane transport
transepithelial transport
ankyrin binding
ammonium transport
regulation of pH
monovalent inorganic cation homeostasis
basolateral plasma membrane
cytoplasmic vesicle
apical plasma membrane
cation transmembrane transport
cellular ion homeostasis
epithelial cell differentiation
cation homeostasis
inorganic ion homeostasis
cellular chemical homeostasis
ion homeostasis
cation transport
cellular homeostasis
ion transmembrane transport
identical protein binding
chemical homeostasis
epithelium development
transmembrane transport
ion transport
integral component of plasma membrane
homeostatic process
tissue development
nitrogen compound transport