RPL10L

Entrez Summary: This gene encodes a protein sharing sequence similarity with ribosomal protein L10. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. This gene is intronless. [provided by RefSeq, Jul 2008].
UniProt Summary: May play a role in compensating for the inactivated X- linked gene during spermatogenesis. {ECO:0000269|PubMed:12490704}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Arsenic trioxide 60μM R08 exp449	-1.89
Pomalidomide 20μM R07 exp391	1.97

ribosomal large subunit assembly
polysome
ribosome assembly
cytosolic large ribosomal subunit
ribosomal large subunit biogenesis
structural constituent of ribosome
ribonucleoprotein complex assembly
ribonucleoprotein complex subunit organization
ribosome biogenesis
translation
peptide biosynthetic process
ribonucleoprotein complex biogenesis
amide biosynthetic process
peptide metabolic process
spermatogenesis
male gamete generation
gamete generation
organelle assembly
cellular amide metabolic process
multicellular organismal reproductive process
sexual reproduction
cellular protein-containing complex assembly
multicellular organism reproduction
multi-organism reproductive process
endoplasmic reticulum
organonitrogen compound biosynthetic process
reproductive process
reproduction
protein-containing complex assembly
cellular nitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
protein-containing complex subunit organization
membrane
gene expression