SERBP1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 24/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	1/28
bone	0/26
breast	1/33
central nervous system	1/56
cervix	0/4
colorectal	2/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	1/20
lung	1/75
lymphocyte	1/16
ovary	1/26
pancreas	0/24
peripheral nervous system	2/16
plasma cell	0/15
prostate	0/1
skin	2/24
soft tissue	0/9
thyroid	1/2
upper aerodigestive	2/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Gene	Correlation
EIF2AK4	0.531
GCN1L1	0.412

PML body organization
SUMO binding
nuclear body organization
mRNA 3-UTR binding
nucleus organization
regulation of mRNA stability
regulation of RNA stability
regulation of mRNA catabolic process
cadherin binding
regulation of mRNA metabolic process
posttranscriptional regulation of gene expression
perinuclear region of cytoplasm
regulation of cellular catabolic process
regulation of catabolic process
RNA binding
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
membrane