SETD4

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
HMS-I1 1μM R01 exp46	-1.77
Rucaparib 6.5μM R08 exp520	1.82

SET
Rubis-subs-bind

peptidyl-lysine monomethylation
protein-lysine N-methyltransferase activity
peptidyl-lysine trimethylation
peptidyl-lysine methylation
protein methylation
protein alkylation
macromolecule methylation
methylation
peptidyl-lysine modification
peptidyl-amino acid modification