SHISA7

Gene Information

Official Symbol: SHISA7
Official Name: shisa family member 7
Aliases and Previous Symbols: N/A
Entrez ID: 729956
UniProt: A6NL88
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 3473
Expression level (log2 read counts): -0.19

Expression Distribution

regulation of AMPA glutamate receptor clustering
regulation of glutamate receptor clustering
asymmetric, glutamatergic, excitatory synapse
regulation of receptor clustering
regulation of postsynaptic neurotransmitter receptor activity
dendritic spine membrane
regulation of postsynaptic membrane organization
regulation of short-term neuronal synaptic plasticity
positive regulation of long-term synaptic potentiation
regulation of AMPA receptor activity
integral component of postsynaptic specialization membrane
AMPA glutamate receptor complex
ionotropic glutamate receptor binding
regulation of long-term synaptic potentiation
regulation of neuronal synaptic plasticity
regulation of glutamate receptor signaling pathway
regulation of neurotransmitter receptor activity
regulation of postsynapse organization
memory
regulation of nervous system process
positive regulation of synaptic transmission
regulation of cation channel activity
regulation of signaling receptor activity
regulation of protein localization to membrane
regulation of synaptic plasticity
postsynaptic membrane
regulation of synapse organization
regulation of synapse structure or activity
postsynaptic density
regulation of ion transmembrane transporter activity
learning or memory
regulation of transmembrane transporter activity
synapse
regulation of transporter activity
cognition
regulation of cation transmembrane transport
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
regulation of ion transmembrane transport
regulation of cellular protein localization