SHROOM1

Entrez Summary: N/A
UniProt Summary: May be involved in the assembly of microtubule arrays during cell elongation. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Vemurafenib 6.6μM R02 exp89	1.72
UM0011500 5μM R05 exp245	1.93

ASD2
ASD1

myosin II binding
apical junction complex
cortical actin cytoskeleton
actin filament bundle assembly
adherens junction
actin filament bundle organization
actin filament binding
actin filament organization
microtubule
apical plasma membrane
supramolecular fiber organization
actin cytoskeleton organization
actin filament-based process
cell morphogenesis
cellular component morphogenesis
cytoskeleton organization