SLC13A1

Entrez Summary: The protein encoded by this gene is an apical membrane Na(+)-sulfate cotransporter involved in sulfate homeostasis in the kidney. Defects in this gene lead to many pathophysiologic problems. [provided by RefSeq, May 2016].
UniProt Summary: Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

CitMHS
Na sulph symp

sodium:sulfate symporter activity
sodium:dicarboxylate symporter activity
tricarboxylic acid transport
citrate transmembrane transporter activity
citrate transport
succinate transmembrane transport
succinate transmembrane transporter activity
succinate transport
sulfate transmembrane transport
sulfate transport
C4-dicarboxylate transport
sulfur compound transport
drug transmembrane transport
dicarboxylic acid transport
inorganic anion transmembrane transport
organic acid transmembrane transport
carboxylic acid transmembrane transport
drug transport
sodium ion transport
inorganic anion transport
anion transmembrane transport
organic acid transport
carboxylic acid transport
monovalent inorganic cation transport
organic anion transport
anion transport
metal ion transport
inorganic ion transmembrane transport
cation transport
ion transmembrane transport
response to drug
transmembrane transport
ion transport