SLC26A2

Entrez Summary: The diastrophic dysplasia sulfate transporter is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias. It apparently is critical in cartilage for sulfation of proteoglycans and matrix organization. [provided by RefSeq, Jul 2008].
UniProt Summary: Sulfate transporter. May play a role in endochondral bone formation. {ECO:0000269|PubMed:7923357}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Sulfate transp
STAS

purine ribonucleoside bisphosphate biosynthetic process
3-phosphoadenosine 5-phosphosulfate biosynthetic process
oxalate transmembrane transporter activity
secondary active sulfate transmembrane transporter activity
oxalate transport
bicarbonate transmembrane transporter activity
sulfate transmembrane transporter activity
chloride transmembrane transporter activity
sulfate transmembrane transport
sulfate transport
anion:anion antiporter activity
microvillus membrane
3-phosphoadenosine 5-phosphosulfate metabolic process
purine ribonucleoside bisphosphate metabolic process
bicarbonate transport
sulfur compound transport
purine nucleoside bisphosphate biosynthetic process
nucleoside bisphosphate biosynthetic process
ribonucleoside bisphosphate biosynthetic process
dicarboxylic acid transport
chloride transmembrane transport
chloride transport
inorganic anion transmembrane transport
ribonucleoside bisphosphate metabolic process
nucleoside bisphosphate metabolic process
purine nucleoside bisphosphate metabolic process
purine ribonucleotide biosynthetic process
purine nucleotide biosynthetic process
inorganic anion transport
ribonucleotide biosynthetic process
ribose phosphate biosynthetic process
purine-containing compound biosynthetic process
sulfur compound biosynthetic process
nucleotide biosynthetic process
nucleoside phosphate biosynthetic process
ossification
anion transmembrane transport
carboxylic acid transport
organic acid transport
purine ribonucleotide metabolic process