SLC27A6

Entrez Summary: N/A
UniProt Summary: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart. {ECO:0000269|PubMed:12556534}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
R-DABN 8μM R03 exp111	-1.85
Tozasertib 0.1μM R07 exp414	1.71

very long-chain fatty acid-CoA ligase activity
long-chain fatty acid transporter activity
long-chain fatty acid-CoA ligase activity
very long-chain fatty acid metabolic process
long-chain fatty acid transport
nucleotide binding
fatty acid transport
sarcolemma
long-chain fatty acid metabolic process
monocarboxylic acid transport
organic acid transport
carboxylic acid transport
lipid transport
lipid localization
fatty acid metabolic process
organic anion transport
monocarboxylic acid metabolic process
anion transport
carboxylic acid metabolic process
cellular lipid metabolic process
oxoacid metabolic process
organic acid metabolic process
lipid metabolic process
ion transport
small molecule metabolic process