SLC30A3

Entrez Summary: N/A
UniProt Summary: Involved in accumulation of zinc in synaptic vesicles. {ECO:0000250|UniProtKB:P97441}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Rapamycin 0.001μM R08 exp429	-1.74
Nifuroxazide 1μM R01 exp51	2.23

ATPase-coupled zinc transmembrane transporter activity
zinc ion import into organelle
zinc ion import into synaptic vesicle
regulation of sequestering of zinc ion
zinc ion transmembrane transporter activity
zinc ion transmembrane transport
zinc ion transport
hippocampal mossy fiber to CA3 synapse
integral component of synaptic vesicle membrane
response to zinc ion
late endosome membrane
synaptic vesicle
transition metal ion transport
late endosome
endosome
divalent metal ion transport
lysosomal membrane
divalent inorganic cation transport
neuron projection
glutamatergic synapse
response to metal ion
response to inorganic substance
cell junction
inorganic cation transmembrane transport
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
ion homeostasis
cation transport
ion transmembrane transport
positive regulation of transport
chemical homeostasis
transmembrane transport
ion transport
integral component of plasma membrane
homeostatic process
regulation of transport
membrane