SLC35A2
Gene Information
- Official Symbol: SLC35A2
- Official Name: solute carrier family 35 member A2
- Aliases and Previous Symbols: N/A
- Entrez ID: 7355
- UniProt: P78381
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2014].
- UniProt Summary: Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 6768
- Expression level (log2 read counts): 4.46