SLC41A1

Entrez Summary: N/A
UniProt Summary: Acts as a magnesium transporter that is responsive to magnesium balance. {ECO:0000269|PubMed:15713785}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Wortmannin 5μM R00 exp38	1.76
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	1.9
Tanespimycin 14μM R08 exp527	1.94

magnesium:sodium antiporter activity
divalent inorganic cation transmembrane transporter activity
cellular magnesium ion homeostasis
cellular response to magnesium ion
magnesium ion homeostasis
magnesium ion transmembrane transport
magnesium ion transmembrane transporter activity
magnesium ion transport
response to magnesium ion
transmembrane transporter activity
sodium ion transmembrane transport
sodium ion transport
cellular response to metal ion
basolateral plasma membrane
cellular response to inorganic substance
divalent metal ion transport
divalent inorganic cation transport
response to metal ion
monovalent inorganic cation transport
cellular divalent inorganic cation homeostasis
divalent inorganic cation homeostasis
response to inorganic substance
cellular metal ion homeostasis
inorganic cation transmembrane transport
protein-containing complex
cation transmembrane transport
metal ion homeostasis
cellular cation homeostasis
metal ion transport
cellular ion homeostasis
inorganic ion transmembrane transport
cation homeostasis
inorganic ion homeostasis
cellular chemical homeostasis
ion homeostasis
cation transport
cellular homeostasis
ion transmembrane transport
chemical homeostasis
transmembrane transport