SLC44A1

Entrez Summary: N/A
UniProt Summary: Choline transporter. May be involved in membrane synthesis and myelin production. {ECO:0000269|PubMed:19357133}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

choline transmembrane transporter activity
choline catabolic process
choline transport
choline metabolic process
amine catabolic process
cellular biogenic amine catabolic process
neurotransmitter catabolic process
organic cation transport
phosphatidylcholine biosynthetic process
ammonium transport
cellular biogenic amine metabolic process
cellular amine metabolic process
amine metabolic process
phosphatidylcholine metabolic process
neurotransmitter metabolic process
mitochondrial outer membrane
neurotransmitter transport
ammonium ion metabolic process
glycerophospholipid biosynthetic process
glycerolipid biosynthetic process
phospholipid biosynthetic process
glycerophospholipid metabolic process
regulation of neurotransmitter levels
phospholipid metabolic process
glycerolipid metabolic process
organophosphate biosynthetic process
lipid biosynthetic process
cation transport
organophosphate metabolic process
cellular lipid metabolic process
organonitrogen compound catabolic process
lipid metabolic process
mitochondrion
transmembrane transport
ion transport
organonitrogen compound biosynthetic process
organic substance catabolic process
cellular catabolic process
nitrogen compound transport
membrane