SLC6A13

Entrez Summary: N/A
UniProt Summary: Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport. {ECO:0000269|PubMed:17502375, ECO:0000269|PubMed:22932902}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
BH1 1μM R04 exp169	1.71
Taxol 0.004μM R03 exp103	1.73

gamma-aminobutyric acid:sodium symporter activity
neurotransmitter binding
gamma-aminobutyric acid transport
amino acid transport
monocarboxylic acid transport
neurotransmitter transport
organic acid transport
carboxylic acid transport
neuron projection
organic anion transport
anion transport
transmembrane transport
ion transport
integral component of plasma membrane
nitrogen compound transport