SORCS3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Gene	Correlation
POLR2J3	0.419
ANKLE1	0.414

regulation of long-term synaptic depression
neuropeptide receptor activity
integral component of postsynaptic density membrane
neuropeptide signaling pathway
memory
learning
regulation of synaptic plasticity
learning or memory
cognition
glutamatergic synapse
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
behavior
G protein-coupled receptor signaling pathway
nervous system process
system process
membrane