STARD10

Entrez Summary: N/A
UniProt Summary: May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes. {ECO:0000250, ECO:0000269|PubMed:15911624}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
GW501516 25μM R06 exp285	-1.91
Arsenate 40μM R06 exp264	-1.73

intercellular canaliculus
bile acid secretion
positive regulation of peroxisome proliferator activated receptor signaling pathway
regulation of peroxisome proliferator activated receptor signaling pathway
phospholipid transporter activity
phosphatidylcholine biosynthetic process
microvillus
phosphatidylcholine metabolic process
acid secretion
phospholipid transport
motile cilium
organophosphate ester transport
monocarboxylic acid transport
lipid binding
ammonium ion metabolic process
glycerophospholipid biosynthetic process
glycerolipid biosynthetic process
phospholipid biosynthetic process
organic acid transport
carboxylic acid transport
lipid transport
glycerophospholipid metabolic process
lipid localization
phospholipid metabolic process
glycerolipid metabolic process
organic anion transport
organophosphate biosynthetic process
lipid biosynthetic process
anion transport
organophosphate metabolic process
cellular lipid metabolic process
secretion
lipid metabolic process
ion transport
organonitrogen compound biosynthetic process
positive regulation of signal transduction
positive regulation of cell communication
positive regulation of signaling
membrane