STX10

Entrez Summary: N/A
UniProt Summary: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. {ECO:0000269|PubMed:18195106}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
ABT-702 0.1μM R06 exp260	1.96
D-Fructose 10000μM R06 exp279	2.21

Syntaxin-6 N
SNARE

early endosome to Golgi transport
SNAP receptor activity
integral component of synaptic vesicle membrane
SNARE complex
syntaxin binding
vesicle docking
SNARE binding
vesicle fusion
endomembrane system
organelle membrane fusion
retrograde transport, endosome to Golgi
trans-Golgi network membrane
organelle fusion
synaptic vesicle
membrane fusion
vesicle
cytosolic transport
organelle localization by membrane tethering
trans-Golgi network
membrane docking
endosomal transport
vesicle organization
Golgi vesicle transport
organelle localization
perinuclear region of cytoplasm
membrane organization
intracellular protein transport
regulation of protein localization
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport