TAS2R13

Entrez Summary: N/A
UniProt Summary: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

taste receptor activity
bitter taste receptor activity
positive regulation of cytokinesis
detection of chemical stimulus involved in sensory perception of bitter taste
sensory perception of bitter taste
detection of chemical stimulus involved in sensory perception of taste
sensory perception of taste
positive regulation of cell division
regulation of cytokinesis
regulation of cell division
positive regulation of cell cycle process
positive regulation of cell cycle
detection of chemical stimulus involved in sensory perception
detection of chemical stimulus
sensory perception of chemical stimulus
detection of stimulus involved in sensory perception
detection of stimulus
G protein-coupled receptor activity
regulation of cell cycle process
sensory perception
regulation of cell cycle
G protein-coupled receptor signaling pathway
nervous system process
system process