TDRD5

Gene Information
  • Official Symbol: TDRD5
  • Official Name: tudor domain containing 5
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 163589
  • UniProt: Q8NAT2
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 12861
  • Expression level (log2 read counts): -5.6

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1