TMED3

Entrez Summary: N/A
UniProt Summary: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. {ECO:0000269|PubMed:10852829}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

COPI vesicle coat
COPII-coated ER to Golgi transport vesicle
endoplasmic reticulum-Golgi intermediate compartment membrane
endoplasmic reticulum-Golgi intermediate compartment
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
transport vesicle
Golgi cisterna membrane
Golgi organization
endoplasmic reticulum to Golgi vesicle-mediated transport
Golgi vesicle transport
endomembrane system organization
Golgi membrane
endoplasmic reticulum membrane
Golgi apparatus
intracellular protein transport
endoplasmic reticulum
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport