TMEM181

Gene Information
  • Official Symbol: TMEM181
  • Official Name: transmembrane protein 181
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 57583
  • UniProt: Q9P2C4
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication. {ECO:0000269|PubMed:19965467}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 14517
  • Expression level (log2 read counts): 7.7

Expression Distribution

  • Last modified: 2026/01/07 22:37
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