UBA7
Gene Information
- Official Symbol: UBA7
- Official Name: ubiquitin like modifier activating enzyme 7
- Aliases and Previous Symbols: N/A
- Entrez ID: 7318
- UniProt: P41226
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Activates ubiquitin by first adenylating with ATP its C- terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein. {ECO:0000269|PubMed:16254333, ECO:0000269|PubMed:20133869}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 13117
- Expression level (log2 read counts): 5.33