UTP11L

Entrez Summary: N/A
UniProt Summary: Involved in nucleolar processing of pre-18S ribosomal RNA. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 59/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	3/28
bone	4/26
breast	3/33
central nervous system	4/56
cervix	0/4
colorectal	3/17
esophagus	0/13
fibroblast	0/1
gastric	2/16
kidney	0/21
liver	1/20
lung	8/75
lymphocyte	1/16
ovary	1/26
pancreas	0/24
peripheral nervous system	5/16
plasma cell	0/15
prostate	0/1
skin	2/24
soft tissue	3/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	1/5

Expression Distribution

small-subunit processome
rRNA processing
rRNA metabolic process
ribosome biogenesis
ncRNA processing
ribonucleoprotein complex biogenesis
ncRNA metabolic process
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
nucleolus
RNA processing
RNA binding
regulation of apoptotic process
regulation of programmed cell death
extracellular space
RNA metabolic process
regulation of cell death
gene expression