UTP14C

Entrez Summary: N/A
UniProt Summary: Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity). {ECO:0000250, ECO:0000269|PubMed:15289605}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Rotenone 2μM R00 exp33	1.91
Phorbol-12-myristate-13-acetate 0.57μM R08 exp514	1.93
Oligomycin-A 20μM R00 exp26	2.52

small-subunit processome
rRNA processing
rRNA metabolic process
meiotic cell cycle
ribosome biogenesis
ncRNA processing
ribonucleoprotein complex biogenesis
ncRNA metabolic process
spermatogenesis
male gamete generation
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
nucleolus
RNA processing
multi-organism reproductive process
cell cycle
reproductive process
reproduction
RNA metabolic process
gene expression