VCY
Gene Information
- Official Symbol: VCY
- Official Name: variable charge Y-linked
- Aliases and Previous Symbols: N/A
- Entrez ID: 9084
- UniProt: O14598
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is a member of a family of human VCX/Y genes. This gene family has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. Members of the VCX/Y family share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. VCX/Y genes encode small and highly charged proteins of unknown function. This gene encodes a small, positively charged protein. The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. [provided by RefSeq, Jul 2008].
- UniProt Summary: May mediate a process in spermatogenesis or may play a role in sex ratio distortion.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 13494
- Expression level (log2 read counts): -7.68
VCY Expression in NALM6 Cells: -7.68
