XK

Gene Information
  • Official Symbol: XK
  • Official Name: X-linked Kx blood group
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 7504
  • UniProt: P51811
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008].
  • UniProt Summary: May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 16772
  • Expression level (log2 read counts): -2.64

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1