ZC3H11A

Entrez Summary: N/A
UniProt Summary: Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex. {ECO:0000269|PubMed:22928037}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Geldanamycin 0.015 to 0.05μM on day4 R07 exp317	-2.1
GSK591 2.6μM R03 exp128	-1.7
UM0129480 7μM R02 exp85	2.01

transcription export complex
poly(A)+ mRNA export from nucleus
mRNA 3-end processing
mRNA export from nucleus
mRNA-containing ribonucleoprotein complex export from nucleus
ribonucleoprotein complex export from nucleus
ribonucleoprotein complex localization
RNA export from nucleus
RNA 3-end processing
protein export from nucleus
mRNA transport
nuclear export
mRNA binding
nucleic acid transport
RNA transport
establishment of RNA localization
RNA localization
nucleobase-containing compound transport
protein-containing complex localization
nucleocytoplasmic transport
nuclear transport
mRNA processing
mRNA metabolic process
RNA processing
intracellular protein transport
RNA binding
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
RNA metabolic process
establishment of localization in cell
nitrogen compound transport
gene expression