UniProt Summary: Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins. {ECO:0000269|PubMed:14656218, ECO:0000269|PubMed:15096500}.
Pfam DomainsGO Terms
Pfam Domains
GoLoco
GO Terms
GTPase regulator activity
positive regulation of cytokine production involved in inflammatory response
regulation of cytokine production involved in inflammatory response
positive regulation of leukocyte chemotaxis
regulation of leukocyte chemotaxis
positive regulation of leukocyte migration
positive regulation of chemotaxis
positive regulation of inflammatory response
regulation of leukocyte migration
regulation of chemotaxis
regulation of inflammatory response
positive regulation of cytokine production
cellular component
positive regulation of defense response
positive regulation of cell migration
positive regulation of cell motility
positive regulation of cellular component movement
positive regulation of locomotion
positive regulation of response to external stimulus
regulation of cytokine production
molecular function
regulation of defense response
regulation of cell migration
regulation of cell motility
regulation of locomotion
regulation of cellular component movement
regulation of response to external stimulus
positive regulation of immune system process
regulation of response to stress
regulation of immune system process
positive regulation of multicellular organismal process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)