HOXA7
Gene Information
- Official Symbol: HOXA7
- Official Name: homeobox A7
- Aliases and Previous Symbols: N/A
- Entrez ID: 3204
- UniProt: P31268
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Pfam Domains GO Terms
Pfam Domains
| Homeobox |
GO Terms
| negative regulation of monocyte differentiation |
| negative regulation of keratinocyte differentiation |
| negative regulation of epidermal cell differentiation |
| negative regulation of epidermis development |
| regulation of monocyte differentiation |
| negative regulation of cell-matrix adhesion |
| regulation of keratinocyte differentiation |
| negative regulation of epithelial cell differentiation |
| negative regulation of leukocyte migration |
| negative regulation of myeloid leukocyte differentiation |
| regulation of epidermal cell differentiation |
| negative regulation of cell-substrate adhesion |
| negative regulation of myeloid cell differentiation |
| regulation of epidermis development |
| embryonic skeletal system morphogenesis |
| RNA polymerase II distal enhancer sequence-specific DNA binding |
| negative regulation of leukocyte differentiation |
| regulation of cell-matrix adhesion |
| regulation of myeloid leukocyte differentiation |
| embryonic skeletal system development |
| negative regulation of hemopoiesis |
| regulation of epithelial cell differentiation |
| stem cell differentiation |
| regulation of leukocyte migration |
| regulation of cell-substrate adhesion |
| anterior/posterior pattern specification |
| regulation of myeloid cell differentiation |
| skeletal system morphogenesis |
| nuclear membrane |
| negative regulation of cell migration |
| regulation of leukocyte differentiation |
| negative regulation of cell adhesion |
| negative regulation of cell motility |
| embryonic organ morphogenesis |
| negative regulation of cellular component movement |
| angiogenesis |
| negative regulation of locomotion |
| transcription factor binding |
| regionalization |
| blood vessel morphogenesis |
| sequence-specific DNA binding |
| embryonic organ development |
| pattern specification process |
| negative regulation of immune system process |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| regulation of hemopoiesis |
| blood vessel development |
| skeletal system development |
| RNA polymerase II proximal promoter sequence-specific DNA binding |
| vasculature development |
| cardiovascular system development |
| embryonic morphogenesis |
| chordate embryonic development |
| embryo development ending in birth or egg hatching |
| tube morphogenesis |
| regulation of cell adhesion |
| negative regulation of cell differentiation |
| tube development |
| regulation of cell migration |
| negative regulation of transcription by RNA polymerase II |
| circulatory system development |
| anatomical structure formation involved in morphogenesis |
| regulation of cell motility |
| negative regulation of developmental process |
| animal organ morphogenesis |
| embryo development |
| regulation of locomotion |
| regulation of cellular component movement |
| negative regulation of transcription, DNA-templated |
| negative regulation of multicellular organismal process |
| positive regulation of transcription by RNA polymerase II |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| negative regulation of RNA metabolic process |
| negative regulation of cellular macromolecule biosynthetic process |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| positive regulation of transcription, DNA-templated |
| negative regulation of biosynthetic process |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| regulation of immune system process |
| negative regulation of gene expression |
| positive regulation of RNA metabolic process |
| regulation of cell differentiation |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 9856
- Expression level (log2 read counts): -2.84
Expression Distribution
HOXA7 Expression in NALM6 Cells: -2.84
