IZUMO1R

• Official Symbol: IZUMO1R
• Official Name: IZUMO1 receptor, JUNO
• Aliases and Previous Symbols: N/A
• Entrez ID: 390243
• UniProt: A6ND01
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate. {ECO:0000250|UniProtKB:Q9EQF4}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 9030
• Expression level (log2 read counts): -7.68

Expression Distribution

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IZUMO1R Expression in NALM6 Cells: -7.68