UniProt Summary: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
Pfam DomainsGO Terms
Pfam Domains
Ion trans 2
Ion trans
K tetra
GO Terms
outward rectifier potassium channel activity
potassium ion export across plasma membrane
calyx of Held
delayed rectifier potassium channel activity
export across plasma membrane
voltage-gated ion channel activity
integral component of postsynaptic membrane
integral component of presynaptic membrane
voltage-gated potassium channel activity
voltage-gated potassium channel complex
potassium ion transmembrane transport
potassium ion transport
membrane raft
axon
protein homooligomerization
glutamatergic synapse
monovalent inorganic cation transport
regulation of ion transmembrane transport
protein complex oligomerization
inorganic cation transmembrane transport
regulation of transmembrane transport
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
regulation of ion transport
cation transport
ion transmembrane transport
export from cell
transmembrane transport
ion transport
protein-containing complex assembly
protein-containing complex subunit organization
regulation of transport
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)