Pfam Domains GO Terms
| Cmyb C |
| Myb DNA-binding |
| Myb complex |
| mitotic spindle assembly |
| positive regulation of neuron apoptotic process |
| mitotic spindle organization |
| positive regulation of neuron death |
| response to leukemia inhibitory factor |
| cellular response to leukemia inhibitory factor |
| spindle assembly |
| microtubule cytoskeleton organization involved in mitosis |
| mitotic nuclear division |
| spindle organization |
| regulation of neuron apoptotic process |
| nuclear division |
| regulation of neuron death |
| organelle fission |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| microtubule cytoskeleton organization |
| RNA polymerase II proximal promoter sequence-specific DNA binding |
| mitotic cell cycle process |
| positive regulation of apoptotic process |
| positive regulation of programmed cell death |
| microtubule-based process |
| DNA-binding transcription factor activity |
| mitotic cell cycle |
| positive regulation of cell death |
| organelle assembly |
| cell cycle process |
| cellular response to cytokine stimulus |
| response to cytokine |
| cytoskeleton organization |
| regulation of cell cycle |
| positive regulation of transcription by RNA polymerase II |
| cell cycle |
| regulation of apoptotic process |
| positive regulation of transcription, DNA-templated |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| regulation of programmed cell death |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| regulation of cell death |
| positive regulation of RNA metabolic process |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 4/28 |
| blood | 10/28 |
| bone | 1/26 |
| breast | 7/33 |
| central nervous system | 4/56 |
| cervix | 1/4 |
| colorectal | 4/17 |
| esophagus | 4/13 |
| fibroblast | 0/1 |
| gastric | 4/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 10/75 |
| lymphocyte | 3/16 |
| ovary | 2/26 |
| pancreas | 1/24 |
| peripheral nervous system | 3/16 |
| plasma cell | 0/15 |
| prostate | 1/1 |
| skin | 0/24 |
| soft tissue | 1/9 |
| thyroid | 0/2 |
| upper aerodigestive | 4/22 |
| urinary tract | 4/29 |
| uterus | 0/5 |
Expression Distribution