SMU1
Gene Information
- Official Symbol: SMU1
- Official Name: SMU1 DNA replication regulator and spliceosomal factor
- Aliases and Previous Symbols: N/A
- Entrez ID: 55234
- UniProt: Q2TAY7
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (PubMed:15878348). Required for normal accumulation of IK (PubMed:24945353). {ECO:0000250|UniProtKB:Q76B40, ECO:0000269|PubMed:15878348, ECO:0000269|PubMed:24945353, ECO:0000305}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 879
- Expression level (log2 read counts): 7.05
SMU1 Expression in NALM6 Cells: 7.05
