UniProt Summary: Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. {ECO:0000269|PubMed:21768292}.
Pfam DomainsGO Terms
Pfam Domains
PTB
PTEN C2
SH2
GO Terms
fibroblast migration
cell-substrate junction assembly
cell junction assembly
ameboidal-type cell migration
cell junction organization
actin binding
cytoskeleton
focal adhesion
cell surface
cell migration
localization of cell
cell motility
locomotion
RNA binding
movement of cell or subcellular component
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)