Pfam Domains GO Terms
| GID complex |
| tertiary granule lumen |
| specific granule lumen |
| ubiquitin ligase complex |
| proteasome-mediated ubiquitin-dependent protein catabolic process |
| proteasomal protein catabolic process |
| neutrophil degranulation |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| myeloid cell activation involved in immune response |
| ubiquitin-dependent protein catabolic process |
| modification-dependent protein catabolic process |
| modification-dependent macromolecule catabolic process |
| myeloid leukocyte activation |
| proteolysis involved in cellular protein catabolic process |
| cellular protein catabolic process |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| protein catabolic process |
| regulated exocytosis |
| leukocyte mediated immunity |
| exocytosis |
| cellular macromolecule catabolic process |
| leukocyte activation |
| secretion by cell |
| export from cell |
| macromolecule catabolic process |
| organonitrogen compound catabolic process |
| cell activation |
| immune effector process |
| secretion |
| proteolysis |
| organic substance catabolic process |
| cellular catabolic process |
| immune response |
| extracellular region |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution